CV Lattes
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ORCID
Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Medicina from Universidade Federal de São Paulo (1981), master's at Nefrology from Universidade Federal de São Paulo (1989) and doctorate at Nefrology from Universidade Federal de São Paulo (1989). Has experience in Medicine, focusing on Nefrology, acting on the following subjects: transplante renal, rejeição aguda, enxerto renal, cicloxigenase and renal transplant. (Source: Lattes Curriculum)
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Chronic kidney diseases are still a leading cause of death worldwide. Thus, the need for new treatment approaches is urgent. Here, we aim to unravel new sensing mechanisms for organelles on renal and immune cells and how the external and internal perception of unbalance is involved in responses which triggers injury, influences repair, and promotes renal tissue fibrosis. We hypothesize th…
Kidney transplantation is one of the most performed transplants worldwide, with Brazil figuring, in 2019, as the second main center concerning the highest procedures numbers. Nevertheless, despite the restricted organ availability, one of the currently challenges across transplantation encompasses the proper graft function. In this sense, ischemia reperfusion injury (IRI) takes a relevant…
It is estimated that between 11 and 13% of the world population has chronic kidney disease (CKD). This scenario is particularly alarming when it is found that it may represent an underestimate ratio, and the diagnosis is usually late, since patients do not usually present complaints except in advanced stages, when renal replacement therapy becomes mandatory. CKD is an indolent and asympto…
(Only some records are available in English at this moment)
Currently, is estimated that the number of Cancer cases and deaths resulting from it is 18.1 and 9.6 million, respectively. The Colorectal Cancer (CRC) is the 3rd type with major incidence. The Colorectal Cancer associated with Colitis is a subtype of CRC related to intestinal inflammatory interaction, difficult treatment and high mortality index. The intestinal epithelial is formed by im…
In recent years, the intestinal microbiota has been the focus of attention due to its role in maintaining homeostasis and its participation in human pathologies. It is known that distant organs such as the kidney have a constant and bidirectional communication with the intestinal microbiota. Thus, both kidney diseases can affect the homeostasis of the microbiota, and metabolites produced …
Renoprotection due to the action of Mxs M2 is primarily mediated by paracrine factors. Additionally, recently it has been shown that Mxs similarly to other eukaryotic cells may release microvesicles (MVs). MVs are defined as vesicles containing membrane fragments with determinate sizes between 100-1000 nm and capacity to carry bioactive molecules. In the case of Mxs, it has been shown tha…
Chronic Kidney Disease (CKD) has high mortality, cardiovascular complications and contributes over 50% of all causes of death in this population. Over 80% of these patients have their treatment subsidized by the Unified Health System (SUS), and 15% of these patients will die on the waiting list for an organ. In Brazil, this incidence and prevalence are increasing, the prognosis remains po…
(Only some records are available in English at this moment)
Evidence suggests that Ulcerative colitis (UC) plays a role in the development of neuroinflammation, increasing the risk of developing cognitive diseases. The gut-brain-microbiota (GBA) is an intricate network connection among neural, microbial, endocrine, and immune systems, that could be mediated by many endocrine factors, including the incretin hormone glucose-dependent insulinotropic …
Chronic Kidney Disease (CKD) is recognized as a global public health problem. CKD is characterized by cellular infiltration into the kidneys, mainly macrophages, which produces growth factors and cytokines that lead to an imbalance between proliferation and apoptosis of tubular cells, promoting activation and proliferation of fibloblasts and consequently kidney fibrosis. The resolution of…
| 1 / 1 | Ongoing grants |
| 11 / 8 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 13 / 5 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 28 / 17 | All research grants and scholarships |
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