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Kelen Cristina Ribeiro Malmegrim de Farias

CV Lattes ResearcherID ORCID  Google Scholar Citations


Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP)  (Institutional affiliation from the last research proposal)
Birthplace: Brazil

Graduated in Pharmacy and Biochemistry from São Paulo State University Júlio de Mesquita Filho (UNESP) in 1997, with a solid academic and scientific trajectory, including international research experience at Radboud University Nijmegen, in the Netherlands (1997-2002). Completed her PhD in Basic and Applied Immunology at the Ribeirão Preto Medical School of the University of São Paulo (FMRP-USP) in 2006, followed by a postdoctoral fellowship (2006-2009) in Applied Immunology and Hematology, also at FMRP-USP.She joined the faculty in 2013 at the School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (FCFRP-USP), where she is currently an Associate Professor III in the Department of Clinical, Toxicological and Bromatological Analyses. She also coordinates the Cell Therapy Laboratory at FCFRP-USP, where she leads research projects focused on advanced therapies and biotechnology applied to health. She teaches undergraduate and graduate courses in Immunology, Hematology, Pathophysiology and Pharmacology of Hematological Diseases, Pharmaceutical Biotechnology, and Immunotherapies. Her teaching and scientific activities emphasize the integration of education, research, and innovation, aiming to train highly qualified professionals and encourage the application of scientific knowledge in innovative therapeutic solutions. In research, she coordinates projects in cell therapy and advanced immunotherapies, focusing on the development and optimization of biotechnological products and processes. Her main research lines include: 1, Cell therapy with hematopoietic stem cells and mesenchymal stromal cells (MSC); 2, Engineering of T cells, NK cells, and Tregs with chimeric antigen receptors (CAR); 3, Autologous and allogeneic stem cell transplantation for immunological and hematological diseases; 4, Development of strategies to enhance the therapeutic properties of MSCs and their extracellular vesicles (exosomes and microvesicles), aimed at clinical and industrial applications; 5, Studies on immunomodulation and immunoregulation involving MSCs, regulatory T cells, and regulatory B cells; 6m Investigation of thymic and bone marrow function, focusing on the hematopoietic microenvironment and thymic niche under physiological and pathological conditions.She is an Associate Researcher at the Center for Cell-Based Therapy (CEPID-FAPESP) and the National Institute of Science and Technology in Stem Cells and Cell Therapy in Cancer (INCT-CNPq-FAPESP). She also supervises master's, doctoral, and postdoctoral students in the Graduate Programs in Biosciences and Biotechnology (FCFRP-USP), Basic and Applied Immunology (FMRP-USP), and Clinical Oncology, Stem Cells, and Cell Therapy (FMRP-USP). In addition to her academic and scientific work, she is actively engaged in science communication, coordinating outreach and communication projects through the FCFRP-USP Science Communication Committee. She also develops science outreach content for social media platforms (@fcfrp and @labterapiacelular on Instagram), helping to bridge the gap between science and society. She maintains strong collaborations with the private sector, leading innovation projects in partnership with the startup In Situ Terapia Celular Ltda, located at Supera Innovation and Technology Park in Ribeirão Preto, reinforcing her commitment to translational innovation and technology transfer to the market. (Source: Lattes Curriculum)

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