CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina (FM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Biology from Universidade São Judas Tadeu (1998) and doctorate at Ciências from Universidade Federal de São Paulo (2006). Has experience in Genetics, focusing on Genetics, acting on the following subjects: deficiência de coenzima q10, doenças mitocondriais, mitochondrial disease, cadeia respiratoria mitocondrial and mitochondria. (Source: Lattes Curriculum)
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Over the last years, CoQ10 deficiencies have been unveiled and the clinical symptoms as well as the molecular mechanisms of the disease have been better understood. CoQ10 is a mobile lipophilic electron carrier localized in the inner mitochondrial membrane and has a critical role in the electron transfer from complex I and II to complex III in electron respiratory chain. In the primary f…
Mitochondrial disorders are highly heterogeneous diseases due to mitochondrial DNA(mtDNA) or nuclear DNA(nDNA) mutations that cause defects of oxidative phosphorylation. These disorders are generally multisystemic and affect highly aerobic post-mitotic tissues, such as muscle and nerve. However, in brazilian hospitals they are generically classified as "respiratory chain defects". In this…
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