CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina Veterinária e Zootecnia (FMVZ) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Veterinary Medicine from University of Sao Paulo, Master of Science in Animal Reproduction also from University of Sao Paulo and obtained the PhD from Michigan State University as a fellow of the CAPES/Fulbright program. Participated in Frontiers in Reproduction course at the Marine Biological Laboratory. Worked as as post-doc in Department of Animal Reproduction at University of São Paulo and in The Hospital for Sick Children in Toronto. Worked as a FAPESP Young Investigator from 2017 to 2020. Currently is an assistant professor in the Department of Animal Reproduction at the University of São Paulo. Acted as 2nd secretary of the Brazilian Society of Embryo Technologies, term 2020-2022. Main focus are developmental biology, reproductive biotechnologies and gene editing. (Source: Lattes Curriculum)
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The first cell differentiation event during mammalian embryonic development results in the formation of the trophectoderm (TE) and the inner cell mass (ICM). For this biological event to occur, there must be spatial and temporal control of the expression of specific transcription factors. This control may involve different types of regulation, including the activation of specific metaboli…
The first events of cellular differentiation occur before embryo implantation in mammals. They consist in the segregation between the inner cell mass and the trophectoderm, followed by segregation between epiblast and primitive endoderm within the inner cell mass. This differentiation process involves different molecular mechanisms, from cell polarization to temporally regulated expressio…
The increase in the number of high genetic value cattle in the national territory depends on the use of reproductive biotechnologies. In vitro embryo production (IVP) allows for a greater number of embryos to be obtained from the same cow compared to in vivo production; however, in vitro-derived embryos exhibit a lower pregnancy rate. During embryonic development, differentiation and form…
The in vitro production of bovine embryos (IVP) has brought significant advances in animal reproduction, allowing the emergence of genetically superior offspring in a short period. However, despite these advances, IVP faces challenges such as low pregnancy rates when compared to in vivo produced embryos. These limitations may be related to the quality of the produced embryos, affecting th…
Biological processes triggered after zygote formation lead to the formation of blastocyst with two established cell lines, internal cell mass (ICM) and trophectoderm (TE), which will give rise to the fetus and placenta, respectively. Understanding the mechanisms involved in this process of cell differentiation in bovine species is essential to obtain better results in in vitro production …
(Only some records are available in English at this moment)
In vitro embryo production (IVP) allows an accelerated genetic improvement of the herd in a short period. However, the pregnancy rates of IVP embryos are still lower than those produced in vivo and may be related to initial cell differentiation. The first cell differentiation event in the embryo determines the inner cell mass and trophectoderm (TE). In mice, the involved biological mechan…
Segregation of cell lines and implantation of the embryo are definitive events for successful gestation. The first cell divisions results in the division between trophectoderm (TE) and inner cell mass (ICM). Following, ICM is then differentiated into epiblast (EPI) and primitive endoderm (PE). It is known that in murine embryos transcription factor NANOG promotes secretion of fibroblastic…
Brazil occupies a prominent position in global production of in vitro bovine embryos. In 2017, the country has established itself as a major exporter of technologies and animal genetics. However, there are still challenges to be overcome in this area.Part of embryo developmental failures may be associated with perturbations in the process of cell differentiation. Prior to embryonic implan…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing grants |
| 1 / 1 | Completed research grants |
| 5 / 5 | Ongoing scholarships in Brazil |
| 11 / 9 | Completed scholarships in Brazil |
| 18 / 16 | All research grants and scholarships |
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