Patrícia dos Santos Costa

Universidade de São Paulo (USP). Instituto de Química (IQ) (Institutional affiliation from the last research proposal)
Birthplace: Brazil

Abstract
The subtilisin serine protease alkaline (AprE) is an important exoprotease enzyme produced by Bacillus subtilis that has important biotechnological applications. In this sense, this project intends to establish a generalized methodology based on CRISPR for genome editing of Bacillus subtilis guided by gRNA using the Case system to carry out targeted mutation in the aprE promoter in order …
Development of a simplified and generalized CRISPR-Cas9 methodology for the optimization of the production of enzymes of industrial interest by bacteria of the genus Bacillus, BP.PD
Abstract
One of the critical steps in the production of cellulosic ethanol by the enzymatic route is the efficient production of glicohydrolases. In this context the objective of this project is to increase the activity of glicohydrolases produced by Trichoderma harzianum P49P11 by culture medium optimization and classic genetic improvement. The promising preliminary results obtained in the master…
Increasing activity of glucohydrolases produced by Trichoderma harzianum by culture medium optimization and classic genetic improvement aiming the viability of ethanol 2G, BP.DD
Abstract
The objective of this work is the genetic improvement of Trichoderma harzianum P49P11 isolated from the Amazon biome and posterior optimization of the culture medium in order to increase cellulases production. The enzymes will be used in the hydrolysis of sugarcane bagasse with the aim of second generation ethanol production. In order to achieve this goal, at first experimental assays wil…
Evolution of T. harzianum strains and performance in submerged bioreactor for the biosynthesis of cellulase for second generation ethanol production, BP.MS

Source:Lattes Curriculum

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3 / 3	Completed scholarships in Brazil

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