Abstract
Recently we demonstrated that Thalassophryne nattereri (Niquim) fish venom induces the formation of a protective immune response characterized by memory B cells (Bmem) and the long-lived antibody-secreting cells (ASC). From a combined in vivo and in vitro approaches we have demonstrated that the generation of ASC (B220neg) on BALB/c mice is related to the production of survival factors fr…