Abstract
Tenofovir disoproxil fumarate and amphotericin B have been associated with nephrotoxicity. Dapagliflozin, an SGLT2 inhibitor, is a novel hypoglycemic drug and its pleiotropic effects have beneficial effects on renal hemodynamics and reducing oxidative stress, inflammation and fibrosis. We aim to investigate whether dapagliflozin can be a therapeutic strategy to mitigate tenofovir and amph…