CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Professor at Department of Structural and Functional Biology, Institute of Biology, State University of Campinas (UNICAMP). Graduated biologist at University of Sao Paulo (2004), Master degree in Sciences (Oncology) at Ludwig Institute for Cancer Research (Sao Paulo Branch - 2006) and PhD degree in Cell and Tissue Biology at University of Sao Paulo (2011). Post-doctoral fellow at Laboratory of Molecular Biology of Thyroid Gland (University of Sao Paulo) from 2012 to 2015. Currently focused on the investigation of the impact of non-coding RNAs, mainly microRNAs and long non coding RNAs, on the modulation of key signaling pathways and its contribution in human pathologies, such as cancer and infertility, through the use of large scale platforms of gene expression, computational approaches and in vitro and in vivo functional analysis. (Source: Lattes Curriculum)
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Papillary thyroid carcinoma (PTC) is the most prevalent histological subtype of thyroid cancer with increasing incidence worldwide. Recently, several studies have shown the abnormal expression of non coding RNAs, such as microRNAs (miRNA) and long non coding RNAs, in different types of cancer, including PTC. We have previously shown the downregulation of several miRNAs from DLK1-DIO3 geno…
Papillary thyroid carcinoma (PTC) is the most prevalent histological subtype of thyroid cancer with increasing incidence worldwide. Recently, abnormal expression of microRNAs (miRNA), emerged as potential diagnostic and prognostic tools for PTC. We have previously shown the downregulation of several miRNAs from DLK1-DIO3 genomic region. This genomic region, mapped at 14q32, harbors severa…
Papillary thyroid carcinoma (PTC) is the most prevalent malignant neoplasia of the thyroid gland. A fraction of PTC cases show loss of differentiation and aggressive behavior, with radioiodine therapy resistance and metastasis. Although microRNAs (miRNAs) emerged as promising molecular markers for PTC, their role in the loss of differentiation observed during PTC progression remains to be…
Thyroid cancer (TC) is the most common endocrine cancer worldwide, with papillary thyroid carcinoma (PTC) being the most frequent histological type. In recent decades, Extracellular Vesicles (EVs) have emerged as a promising alternative in cancer treatment, as they have been described as transport tools for various molecules, including miRNAs. In this context, the administration of exosom…
Thyroid cancer is the main type of neoplasia of the endocrine system and its incidence is increasing worldwide in the last decade. The most prevalent subtype is the papillary thyroid carcinoma (PTC), which is mainly affected by abnormal MAPK signaling activation. Recently, abnormal expression of microRNAs (miRNA) emerged as potential diagnostic and prognostic tools for PTC. We have previo…
Conjugal infertility is the inability of conceiving after one year of regular sexual activities without using contraceptive methods. Assisted Human Reproduction (AHR) procedures, which include Controlled Ovarian Hyperstimulation (COH) followed by Intracytoplasmic Sperm Injection (ICSI), are the best treatment options. However, variable responses to the COH protocols are obtained, ranging…
Thyroid Carcinoma is the most common Endocrine Cancer worldwide, with Papillary Thyroid Carcinoma (PTC) being the most prevalent histotype, comprising more than 80% of the cases. In recent years attention has been focused on the role of microRNAs (miRNAs), small non-protein encoding RNAs, in the biology of tumor cells, especially in the role of these molecules in the modulation of pathway…
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The knowledge obtained in the past few years concerning non-coding RNAs (ncRNAs) has changed majorly our perception about their role in cell biology. Thought to be part of what was once called "junk transcripts", ncRNAs have revealed to play important regulatory functions within cells, mediating all cellular processes. The human chromosome 14 bears several ncRNA genes, including one of th…
| 1 / 1 | Ongoing grants |
| 4 / 2 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 7 / 5 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 14 / 10 | All research grants and scholarships |
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