André Luis Bombeiro

• Abstract

  Peripheral nerve injury leads to disruption of the nerve and interruption of impulse transmission. However, if the perineurium surrounding the lesion is preserved, axonal regeneration following degeneration of the distal stump, a process named Wallerian degeneration, is possible. Participation of Schwann cells in myelin debris removal is an important step because axonal growth inhibitors …

  Axonal regenerative potential of GM-CSF in C57BL/6 mouse peripheral nerve, BP.IC

• Abstract

  A growing number of studies have demonstrated the involvement of the major histocompatibility complex class I (MHC-I) molecules in distinct processes of antigen presentation to the cytotoxic T cells (T CD8) of the immune system. Although the expression of MHC-I molecules by neurons is low in basal conditions, it has been demonstrated that these cells are able to significantly enhance the …

  The involvement of the major histocompatibility complex class I molecules in the astrocytic reactivity after sciatic nerve transection, BP.IC

• Abstract

  The class I major histocompatibility complex (MHC-I), which is present in all nucleated cells, is mostly known to present endogenous antigens to cytotoxic T lymphocytes (CTLs) from the immune system. In the central nervous system (CNS), the participation of the MHC-I in the synaptic plasticity process has been suggested. MHC-I is overexpressed on the neurites of damaged neurons and acts …

  The involvement of major histocompatibility class I molecules in the synaptic plasticity, glial reactivity and axonal regeneration, BP.PD

(Only some records are available in English at this moment)