CV Lattes
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Secretaria da Saúde (São Paulo - Estado). Instituto Butantan (Institutional affiliation from the last research proposal) Birthplace: Brazil
Karen de Morais Zani holds a bachelor's degree in Biological Sciences from Universidade Presbiteriana Mackenzie (2006). She joined Instituto Butantan in 2004, where she conducted scientific initiation, master's, doctoral, and post-doctoral studies. She obtained a master's degree in General Physiology from the Institute of Biosciences at the University of São Paulo (2009) and a PhD in Biotechnology from the Interunits Program in Biotechnology of the University of São Paulo/Institute of Technological Research/Butantan Institute (2013), with a sandwich period at the University of Lille (Lille, France). Currently, she is a researcher at the Pathophysiology Laboratory of Instituto Butantan, focusing primarily on Toxinology, with emphasis on the compositional and functional characterization of snake venoms. (Source: Lattes Curriculum)
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Snake envenomation is classified by the World Health Organization as a neglected tropical disease. In Brazil, 25,115 cases of snakebites by venomous snake species were recorded in 2023. Around 87% of these accidents are attributed to snakes of the genus Bothrops whereas 10% are attributed to the genus Crotalus. Snake venoms are complex mixtures of proteins, with variable composition among…
Snakebite envenoming constitutes a highly relevant public health problem on a global scale. It primarily affects impoverished populations in the rural settings of Africa, Asia, Latin America and parts of Oceania, and is classified as a neglected tropical disease by the World Health Organization. In Brazil, the genus Bothrops is responsible for approximately 85% of the reported snakebite a…
Snakebite accidents are classified by the World Health Organization as a neglected tropical disease responsible for approximately 2.5 million cases of envenomation and 150,000 deaths per year, especially in rural regions of Africa, Asia, Latin America and Oceania. In Brazil, the Viperidae family represents the most important group of snakes for public health, as they are responsible for t…
(Only some records are available in English at this moment)
Snakebite envenoming is classified as a Neglected Tropical Disease by the World Health Organization, primarily affecting impoverished populations in rural areas of Africa, Asia, and Latin America. In Brazil, 25,115 snakebite cases were reported in 2023, 86% of which were caused by the Bothrops genus. The severity of snakebite accidents caused by Bothrops species is a significant public he…
In 2023, in Brazil, 32,420 snakebite incidents were reported, with two-thirds of these occurrences happening in the North and Northeast regions, which also had the highest number of deaths due to snake envenomations that year. The only effective treatment for these envenomations is antivenom serum, produced by injecting animals with pools of different species of the snake genus relevant t…
Snake envenomation is classified by the World Health Organization as a neglected tropical disease responsible for approximately 2.5 million envenomations and 150,000 deaths per year, especially in rural regions of Africa, Asia, Latin America and Oceania. In Brazil, the Viperidae family represents the most important group of snakes for public health, as they are responsible for most of the…
The suborder Serpentes includes animals with an elongated body, which move by undulations without the presence of anterior locomotor limbs. Snake venom is a toxic secretion, with several proteins and mechanisms of action, such as neurotoxic, myotoxic and coagulant. Within the Suborder Serpentes there is the family Elapidae, to which the genus Micrurus belongs. Micrurus is an abundant and …
According to the World Health Organization (WHO), the number of snakebites per year reaches approximately 5.4 million, resulting in between 81,000 and 138,000 deaths and 400,000 people who are incapacitated by the envenomation. According to the Ministry of Health, there are approximately 19,000 to 22,000 snakebites per year in Brazil, and snakes of the genus Bothrops, of the Viperidae fam…
The venom of venomous animals is composed of a wide range of enzymes, biologically active peptides and other toxins that have a varied toxic effect on the body, including coagulation, fibrinolysis and altered platelet functions. In extreme cases, it can even lead to multiple organ failure and disseminated intravascular coagulation (DIC), thus demonstrating a need to conduct research and d…
(Only some records are available in English at this moment)
Snakebite accidents is classified by the World Health Organization as a neglected tropical disease responsible for approximately 2.5 million cases of envenomation and 150,000 deaths per year, especially in rural regions of Africa, Asia, Latin America and Oceania. In Brazil, the Viperidae family represents the most important group of snakes for public health, as they are responsible for th…
Antithrombin is a plasma glycoprotein belonging to the serpin family that plays a key role in controlling hemostasis, acting as an important inhibitor of blood coagulation by inactivating thrombin and other serine proteases, such as factors VIIa, IXa, Xa, XIa and XIIa. In addition to participating as a major physiological inhibitor of blood coagulation, antithrombin has anti-inflammatory …
| 1 / 1 | Ongoing grants |
| 5 / 5 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 9 / 7 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 20 / 18 | All research grants and scholarships |
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