Sergio Luiz Domingues Cravo

• Abstract

  Obstructive sleep apnea is the most common sleep disturbance, affecting up to 33% of the adult population. Numerous studies have shown that OSA can induce and/or aggravate cardiovascular syndromes such as arterial hypertension, congestive heart failure, arrhythmias, etc. The mechanisms that cause or exacerbate these syndromes are still not clear. The animal models used currently to study…

  Development of an experimental model of obstructive sleep apnea in rats, AP.R
• 6th Congress of The International Society for Autonomic Neuroscience, AR.EXT
• Role of medullary glutamatergic and purinergic p2x receptors in cardiovascular adjustments during defense reactions., AR.EXT

(Only some records are available in English at this moment)

• Abstract

  The obstructive sleep apnea (OSA) is the most common sleep disorder, and is related to arterial hypertension. Among the mechanisms proposed to explain this relationship is sympathetic overactivity. Our laboratory has developed a model of OSA in rats using an intratracheal balloon to cause upper airway occlusion. The objective of this study is to verify whether there is changes in blood pr…

  Cardiovascular adaptations induced by a chronic model of obstructive sleep apnea in rats, BP.PD