CV Lattes
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Universidade Paulista (UNIP). Vice-Reitoria de Pesquisa e Pós-Graduação (Institutional affiliation from the last research proposal) Birthplace: Brazil
Anuska received her Biological Sciences degree (2007) from UNESPs Bauru School of Sciences, São Paulo State University, Brazil and she argued her PhD thesis (2013) at the Graduate Studies Program in Microbiology and Immunology of Paulista Medical School, Federal University of São Paulo, Brazil. She was a postdoctoral fellow at Paulista University (2013-2017) and at Cruzeiro do Sul University (2017-2022) collaborating with Butantan Institute (2019-2021). Currently, she is a Full Professor at the Graduate Studies Program in Environmental and Experimental Pathology, Research Center from Paulista University, Brazil. She has experience in Immunology and Microbiology, focusing on Cellular Immunology, Immunopathology, Immune regulation, Immunometabolism, Autoimmunity, Parasite-host relationship, immune response in infections. She was the first to demonstrate the ability of B-1 lymphocytes to produce insulin and her research group is focused on a protocol for metabolic reprogramming B-1 cells to alow a cellular therapy that is able to regulate the glycemia of individuals with Diabetes. (Source: Lattes Curriculum)
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Introduction: B-1 lymphocytes are well-known for their ability to differentiate into plasmocytes and secrete natural IgMs, but research has demonstrated their pluripotent potential, allowing them to differentiate into other cell types. A 2015 study revealed that these cells are capable of producing insulin and controlling glycemic levels in diabetic mice. In that experiment, XID mice with…
Introduction: B-1 lymphocytes are a subpopulation of B lymphocytes which was identified firstly in chronic lymphocytic leukemia patients. Since then, several research has demonstrated pluripotent cells characteristics, differentiating into different cell types. In 2015, the ability to produce insulin and glycemic control in diabetic mice was demonstrated after adoptive cells transfer. Pre…
The candidate (Alvares-Saraiva et al., 2015) demonstrated, for the first time, a regulatory role of B-1 lymphocytes in the control of glycemia in Type I Diabetes streptozotocin (STZ)-induced. As the main point, the adoptive transfer of B-1 lymphocytes from WT mice to XID mice (deficient in B-1 lymphocytes) has become them resistant to Diabetes induction. Also, insulin-producing cells were…
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