CV Lattes
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Universidade de São Paulo (USP). Instituto de Química (IQ) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Biological Sciences from Universidade Presbiteriana Mackenzie (2004), Master in Sciences (Cell and Tissue Biology) from Universidade de São Paulo (2008), PhD in Sciences (Cell and Tissue Biology) from Universidade de São Paulo (2013), approved by the Department of Cell Biology and Pathology at the Universidad de Salamanca (2014), Post-doctorate in Biochemistry by the University of São Paulo (2020). Currently, works as a postdoctoral researcher at the Center for Genomics and Systems Biology in the Department of Biology at New York University (NYU).Main interests include: proteostasis (protein degradation, via ubiquitin-proteasome, E3 ligases, chaperone-dependent degradation), physiological models (3D culture, organoids, IPSc differentiation), signaling pathways (MAPK, TGFb, Hippo, Wnt). (Source: Lattes Curriculum)
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The composition and organization of the extracellular matrix (ECM) and tissue architecture are crucial microenvironment components that produce biochemical and mechanical signals that can initiate and sustain asymmetrical patterns of proliferation an invasion in several tissues, including mammary gland epithelia. However, it remains uncertain which intracellular pathways/molecules connect…
Chemical and mechanical signals from the basement membrane (BM), an extracellular matrix compartment (ECM), reprogram gene expression leading to quiescence and differentiation of mammary gland epithelial cells. Hippo-YAP, a pathway that regulates organ growth and size, act as a "relay" for mechanical signals from the microenvironment. It is known that the inhibition of HIPPO kinases allow…
| 2 / 1 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 3 / 2 | All Scholarships |
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