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Carolini Kaid Dávila

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Universidade de São Paulo (USP). Instituto de Biociências (IB)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

Completing 10 years of experience in cancer biology research, the academic training at Institute of Bioscience, University of São Paulo, has provided an excellent background in multiple biological disciplines including CNS tumor research, tumor stem cells, and advanced therapies. During her MsC, the work with miR-367 as a biomarker for aggressive pediatric cancer and potential therapeutic target led to the 2015 Award of Scientist and Entrepreneurial of the Year, by Nanocell Institute. As PhD student, under the mentorship of Dr. Oswaldo Keith Okamoto, she acquired a broad background in preclinical models with specific training and expertise in cell culture, brain histology, molecular genetics, stereotaxic surgery, and stereology. The PhD Thesis, awarded with Brazil?s Best PhD Thesis 2020 by CAPES, resulted in two patents applications and preclinical findings that open opportunities for future translational studies to evaluate new putative biomarkers of aggressive stem-like tumor cells in refining diagnosis, patient stratification, and early detection of relapsed disease, while also revealing novel therapeutic approaches, using the miR-367 inhibitor and the oncolytic Zika virus, both targeting the stem-like tumor cells that could benefit patients affected by CNS tumors lacking effective treatment. Recently, as postdoctoral fellow at Human Genome and Stem Cell Research Center, under Dr. Mayana Zatz supervision, she continues to investigate alternative immunotherapies with a focus on oncolytic viruses and is coordinating a veterinary clinical trial using the oncolytic Zika virus in dogs with advanced brain tumors. (Source: Lattes Curriculum)

News published in Agência FAPESP Newsletter about the researcher
FAPESP support in numbers * Updated July 24, 2021
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Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (3)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Data from Web of Science

KAID, CAROLINI; SILVA, PATRICIA B. G.; CORTEZ, BEATRIZ A.; RODINI, CAROLINA O.; SEMEDO-KURIKI, PATRICIA; OKAMOTO, OSWALDO K.. miR-367 promotes proliferation and stem-like traits in medulloblastoma cells. Cancer Science, v. 106, n. 9, p. 1188-1195, . Web of Science Citations: 23. (13/02983-1, 14/10519-6, 11/10001-9, 13/08028-1, 13/17566-7, 10/52686-5)

KAID, CAROLINI; JORDAN, DIONE; DE SIQUEIRA BUENOS, HELOISA MARIA; SILVA ARAUJO, BRUNO HENRIQUE; ASSONI, AMANDA; OKAMOTO, OSWALDO KEITH. miR-367 as a therapeutic target in stem-like cells from embryonal central nervous system tumors. MOLECULAR ONCOLOGY, v. 13, n. 12, . Web of Science Citations: 0. (13/08028-1, 13/02983-1, 16/09707-8, 14/08049-1)

GONCALVES DA SILVA, PATRICIA BENITES; TEIXEIRA DOS SANTOS, MARCIA CRISTINA; RODINI, CAROLINA OLIVEIRA; KAID, CAROLINI; LEITE PEREIRA, MARCIA CRISTINA; FURUKAWA, GABRIELA; GIMENES DA CRUZ, DANIEL SANZIO; GOLDFEDER, MAURICIO BARBUGIANI; REILY ROCHA, CLARISSA RIBEIRO; ROSENBERG, CARLA; et al. High OCT4A levels drive tumorigenicity and metastatic potential of medulloblastoma cells. ONCOTARGET, v. 8, n. 12, p. 19192-19204, . Web of Science Citations: 3. (13/02983-1, 11/10001-9, 13/08028-1, 13/17566-7, 10/52686-5, 11/51588-2, 11/05534-8)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

DÁVILA, Carolini Kaid. Expressão de hsa-miR-367 e agressividade de meduloblastoma humano. Dissertação (Mestrado) -  Instituto de Biociências.  Universidade de São Paulo (USP).  São Paulo.  (13/02983-1

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