CV Lattes
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Universidade de São Paulo (USP). Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
He is currently PhD Professor in the field of Biochemistry in the Department of Chemistry (DQ) linked to the Faculty of Philosophy, Sciences and Letters of Ribeirão Preto (FFCLRP) - University of São Paulo (USP), head (PI) of the GeBIL- Study Group in Biotechnology and Immunochemistry of Lipids and advisor of Master / Doctorate of graduate courses. Undergraduated in Chemistry - (Modalities: Bachelor's, and biotechnological assignments) from the Faculty of Philosophy, Sciences and Letters of Ribeirão Preto (FFCLRP) -Universidade de São Paulo (USP) (2002); Doctorate by the Faculty of Medicine of Ribeirão Preto (FMRP) - USP (2006) - Department of Biochemistry and Immunology - Biochemistry Program; Post-doctorate by CNRS -UMR6218 -Molecular Immunopharmacology - Transgenose Institut- Université du Orleans- France (2011-2012); Sandwich postdoctoral fellow at the University of Colorado- Denver - USA and Faculty of Pharmaceutical Sciences of Ribeirão Preto - USP (2014 - 2016) with an emphasis on Biochemical and Molecular Pharmacology. Worked as a Laboratory Specialist (category S3) at the Faculty of Pharmaceutical Sciences of Ribeirão Preto (FCFRP) - USP (2003-2020); Has scientific experience in the field of Biochemistry; Biochemical and Molecular Pharmacology; Immunology. Emphasis on Tumor Metabolism; Inflammation; Mass Spectrometry applied to biomolecules (Lipidoma and Metaboloma) and Enzymology of cellular metabolism. He also works on projects with partnerships in the Medical and Dental Clinic. He was technically responsible for Ceqil - Center of Excellence in Lipid Quantification and Identification - FCFRP- USP. Member of university commissions, congregation, advisor to FAPESP and international scientific journals, as well as Guest Editor. (Source: Lattes Curriculum)
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Matrix metalloproteinases (MMPs) are key regulators of extracellular matrix remodeling and inflammation through proteolytic processing of cytokines and chemokines. Diversal MMPs are expressed by macrophages and contribute to development and progression of many diseases including cancer, autoimmune diseases, and atherosclerotic cardiovascular disease. Indeed, it is suggested that some nove…
Sphingolipids (SL) are structurally and functionally diverse molecules with important physiological functions, found associated with cell membranes, plasma lipoproteins, or extracellular vesicles (EV). Concentrations of SL are altered in various metabolic disorders such as obesity, implicating the regulation of inflammation, apoptosis, cell proliferation, autophagy, and insulin resistance…
Lipids represent the majority of biomolecules comprised in metabolomics. In this sense, a functional lipidomic configures an integrative strategy for the identification of bioactive lipids, membrane lipids composition, interactions of lipids with signaling proteins and metabolism enzymes. Consequently, lipids can influence pathological processes, such as inflammation and signaling of the …
(Only some records are available in English at this moment)
Metabolic Dysfunction-Associated Steatohepatitis (MASH) represents a growing public health challenge, with an alarming global prevalence and progression to severe stages such as cirrhosis and hepatocellular carcinoma. Sexual dimorphism in MASH influences susceptibility, progression, and treatment response, requiring in-depth investigation. Recent evidence from our research group indicates…
The space race, initiated during the Cold War (between 1957 and 1975), marked the beginning of the era in which humanity broke the barriers of planet Earth. Yuri Gagarin, a Soviet cosmonaut, became the first human to travel into space aboard Vostok 1. Later, Neil Armstrong and Buzz Aldrin, on the Apollo 11 mission, were the first to walk on the Moon, consolidating human potential for expl…
Sphingolipids (SL) are structurally and functionally diverse molecules with important physiological functions, found in cell membranes as well as in plasma lipoproteins or extracellular vesicles (EVs). Plasma concentrations of these SL can fluctuate in response to metabolic disorders and may serve as predictive biomarkers of diseases or mediators in the regulation of immune responses. In …
(Only some records are available in English at this moment)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-19 pandemic, with serious consequences for affected individuals and society as a whole. The biology and infection process of the virus have been intensively studied to gain a better understanding of the molecular basis of virus-host cell interactions. SARS-CoV-2 is known to bind to angiotensin-convertin…
SARS-CoV-2 infection has become a worldwide public health concern, severely affecting our society and economy, due to the disease's long incubation time and high prevalence. Thus, efforts were made to develop vaccines and antiviral treatments. The entry of SARS-CoV-2 into cells depends on binding to its ACE-2 receptor, triggering inflammatory cascades that are linked to the pathophysiolog…
Macrophages (MAs) are cells widely distributed by tissues, participating in various biological processes. These cells play an important role in inflammation with the production of cytokines and lipid mediators. For the activation of MA, the presence of soluble factors in the cellular microenvironment is necessary, polarizing them in two distinct patterns: classical activation (M1) or alte…
Many individuals infected with the severe acute respiratory syndrome virus coronavirus-2 (SARS-CoV-2) develop only mild symptoms, but some could develop a spectrum of severe symptoms. Although little understanding of the immunopathology of SARS-CoV-2, it is well described that this mechanism was associated with hyperinflammation, tissue damage and disruption of host target organ metabolis…
Inflammation is necessary for life and mostly beneficial, but sometimes inflammatory reactions can become excessive, and lead to harmful outcome. In several endemic diseases chronic inflammation is part of the pathophysiology. 5-Lipoxygenase (5-LO) has a central role in the biosynthesis of leukotrienes (LTs) an important inflammatory mediators. LTs responses, which are often thought to ha…
| 2 / 2 | Ongoing grants |
| 6 / 6 | Completed research grants |
| 4 / 4 | Ongoing scholarships in Brazil |
| 3 / 3 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 17 / 17 | All research grants and scholarships |
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