Abstract
In rats with type 1 diabetes induced by streptozotocin (STZ) alterations in proteoglycans, sindecan-4 and glipican-1 in cardiac tissue occurs concomitantly to the installation of diastolic dysfunction, early event culminating in diabetic cardiomyopathy. In this study, however, was not established whether the changes in contractile function of the hearts can be attributed directly to chang…