CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Farmacêuticas (FCF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Pharmacist (USP-2007), PhD in Sciences (USP-2011), with a Doctorate internship at Boston University, MA, USA (2009). Associate Professor of Pharmaceutical Technology at the State University of Campinas (Unicamp) and current Associate Coordinator of the Postgraduate Program in Pharmaceutical Sciences at Unicamp. Works in the area of #8203;#8203;pharmaceutical technology, focusing on the delivery of active pharmaceutical ingredients through nanostructured and lyophilized systems. Reviewer for funding agencies in Brazil and abroad and several journals in the area of #8203;#8203;Pharmacy. Associated with the Brazilian Academy of Pharmaceutical Sciences, the Controlled Release Society and the Regional Council of Pharmacy. Associate coordinator of the undergraduate pharmacy course: 2016-2020. President of the Structuring Teaching Nucleus: 2022-2024. (Source: Lattes Curriculum)
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Community-acquired pneumonia (CAP) has the highest mortality among current infections. Despite being predominantly bacterial, one third of the global cases of CAP had a viral etiology, referring to approximately 100 million cases (2016). In 2019-2020, the respiratory virus Sars-Cov-2 alone caused 280 thousand deaths in 215 countries (until 12/05/2020, the vast majority with cases of pneum…
Leishmania species infect at least 10 million people worldwide. Cutaneous leishmaniasis, a disease that causes skin ulceration and deformities, has 70% of its global burden concentrated in the Americas, whereas Brasil contributes to more than 12%. Some protozoan species presented resistance to N-Methyl-D-glucamine, the most disseminated treatment for leshmaniasis. It is likely that resist…
Pneumonia is a pathology that can be caused by bacteria, viruses or fungi, which infect the alveolar tissues, compromising the patient's breathing through increased mucus secretion, which makes gas exchange difficult. This clinical condition has great relevance in Brazil and in the world, representing eighteen percent of the cause of death in children, according to the World Health Organi…
Respiratory tract infections are the main cause of mortality from infectious diseases in the world and in Brazil, even before the pandemic. Etiological agents include bacteria, which are resistant to various antibiotics and impair their eradication. In particular, chronic lung infections are often fatal to patients with cystic fibrosis, whose disease severity is related to biofilms in the…
Nanostructured lipid carriers (NCL's) are stable, scalable, biodegradable drug carriers that are administered by different routes of administration. These nanostructures often rely on surfactants for their colloidal stability, but amphiphilic molecules also influence the fate and release of the delivered drug. Adsorption of protein on nanoparticle surface, depending on the amount and type…
Recent researches have shown that, in general, the combined treatment of antibiotics exhibits greater performance than monotherapies. In particular, the treatment of bacterial infections that may cause meningitis - a disease that presented nearly 110 thousands new cases between 2000 and 2010 in Brazil - showed superior results of the combined treatment with ceftriaxone and levofloxacin, w…
Exposure to bisphosphonates, antiangiogenic agents and radiotherapy may lead the dental patient to a medication-related osteonecrosis of the jaw (MRONJ). Bacterial infection plays an important role in the development of this disease; thus, oral formulations with antimicrobials may be prophylactic and therapeutic for such clinical condition. Nanotechnology can optimize the delivery of acti…
(Only some records are available in English at this moment)
Doxycycline (DX) is well recognized for its broad-spectrum antibiotic properties and anti-inflammatory effects, what makes it a relevant therapeutic agent for various lung diseases, including chronic obstructive pulmonary disease, asthma, and pneumonia. DX's bioavailability and safety profile justify its use in respiratory conditions, while its side effects are generally mild compared to …
The pulmonary drug delivery can benefit local therapy for lung diseases by promoting high concentration of the drug in the site of action and rapid effect onset. Concerning treatment of bacterial infections, Levofloxacin (fluoroquinolone) stands out as a broad-spectrum agent and effective for invasions of the respiratory tract; it has also pulmonary delivery approved by European Union and…
Antibiotics constitute the main treatment component for lung infections, wich includes Doxycycline (DX). This antimicrobial drug acts against gram-positive and gram-negative microorganisms, besides aiding in inflammation control. Pulmonary delivery may enhance local targeting and decrease systemic effects, but drugs cannot permeate quickly. To address drug distribution and retention, PLGA…
| 6 / 3 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 5 / 5 | Completed scholarships in Brazil |
| 3 / 3 | Completed scholarships abroad |
| 16 / 13 | All research grants and scholarships |
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