Abstract
The epithelial-mesenchymal transition (EMT) is an important event in a series of steps that result in tissue fibrosis. The transdifferentiation is the process by which renal and extrarenal cells, affected by cytokines released during the inflammatory process such as TGF-² (transforming growth factor-²), angiotensin II and endothelin, modify their phenotype and start to produce extracellul…