CV Lattes
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Universidade Federal de São Carlos (UFSCAR). Centro de Ciências Exatas e de Tecnologia (CCET) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Química from Universidade Federal de Juiz de Fora (2007). Has experience in Chemistry, focusing on Inorganic Chemistry, acting on the following subjects: palladium, total atomic charges, infrared spectroscopy and dft calculation. (Source: Lattes Curriculum)
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In vitro cell cultures are fundamental techniques in developing new drug candidates1. Traditional cell culture methods use a two-dimensional (2D) monolayer. Today, this method has become standard technology in the life sciences, making continuous improvements. However, due to the inherent flaws of traditional 2D culture, this methodology cannot correctly mimic the architecture and microen…
In vitro cell cultures are fundamental techniques in developing new drug candidates. Traditional cell culture methods use a two-dimensional (2D) monolayer. Today, this method has become standard technology in the life sciences, making continuous improvements. However, due to the inherent flaws of traditional 2D culture, this methodology cannot correctly mimic the architecture and microenv…
DNA-topoisomerases enzymes are one of main biological targets against cancer. These proteins participate of different nuclear processes. Literature shows that some types of cancer have a great expression of the topoisomesae I² (TOPO1B) and/or topoisomesae II± (TOPO2A). However, few studies were performed to prove the quantities of the enzymes inside the cells. Thus, this Project has the o…
(Only some records are available in English at this moment)
Cancer is a term used to describe a group of diseases that can affect any part of the body, one of the main characteristics of which is rapid growth beyond what is considered normal. Approximately one in six people die from various forms of the disease, making it the second leading cause of death worldwide. To reduce the mortality rate, various treatments are used to combat the diseases, …
Cancer arises from a genetic mutation that occurs inside of the nucleus of the cell, different types of cancer are the second cause of the death in the world. In fact, one each six deaths are related to the disease. Although only 3 complexes are approved for clinical use, currently, Pt (II) compounds participate in approximately 50% of cancer treatments. However, these compounds have seve…
This project aims the synthesis , characterization of new complexes of general formula [ PdX ( TSC ) ( PPh3 ) ] TSC = { ( 2E ) -2 - [ ( 2E ) - 3 - phenyl - 1 - ylidene ] hydrazinecarbothioamide ; 2E- N-methyl- 2-[( 3 (E )-4- phenyl-3- butene -2-ylidene ] hydrazinecarbothioamide , X = Cl, I, SCN, SeCN, NNN } and evaluation of the inhibitory capacity against topoisomerase II±. The interacti…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing grants |
| 4 / 4 | Completed research grants |
| 4 / 4 | Completed scholarships in Brazil |
| 9 / 9 | All research grants and scholarships |
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