Abstract
Duodenal ulcer-promoting gene A (dupA), is a novel virulence factor, in Helicobacter pylori and was associated with duodenal ulcer development and reduced risk for gastric carcinoma in some populations. In addition, E-caderin gene seems to be associated with the infiltrative and metastatic ability of gastric tumors. Previous studies suggest that gene inactivation of E-cadherin by H. pylor…