Abstract
In previous studies, we demonstrated that lipid nanoparticles with a lipid structure similar to low-density lipoprotein (LDL), termed LDL-like nanoparticles (LDE), accumulate in transplanted rabbit hearts. When rabbits with cardiac transplants, a model of graft vascular disease (GVD), were treated with the chemotherapeutic agent paclitaxel associated with LDE, there was a notable reductio…