CV Lattes
Abstract
Streptococcus pneumoniae is an important human pathogen, causing severe diseases such as meningitis, pneumonia, bacteremia and sepsis. The currently avaliable vaccines induce anti-capsular polysaccharide antibodies and have some disadvantages, such as limited serotype coverage and high production costs. The widespread use of the 7-valent conjugate polysaccharide vaccine led to a drastic r…