CV Lattes
Universidade de Franca (UNIFRAN). Pró-Reitoria Adjunta de Pesquisa e Pós-Graduação (Institutional affiliation from the last research proposal) Birthplace: Brazil
Fernanda Rafacho Badoco in research grants and scholarships supported by FAPESP.
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Schistosoma mansoni is a parasite which leads to a condition known as schistosomiasis due to granulomatous reactions formed around the parasite eggs which migrate to the host tissue. The only drug used for the treatment against the parasite is praziquantel, due to its effectiveness, but there are already reports of parasite resistance against the action of the drug. About its mechanism of…
Curcumin, which is a phenolic compound extracted from the rhizome of the plant Curcuma longa show schistosomicidal activity both in vitro and in vivo. Moreover, further studies with other organisms have shown that curcumin is a potent apoptotic agent. However, there are several limitations, which may restrict their use of curcumin, as a potential substance for treatment of several disease…
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