Abstract
Paracoccidioides spp. fungi are pathogenic, thermally dimorphic and ethiologic agents of Paracoccidioidomycosis (PCM), the major mycosis in Latin America. The infected individual with Paracoccidioides spp. develops a response against the fungus as a way to eliminate it from by organism. The resistance to P. brasiliensis infection is associated with secretion of high levels of TNF-± and IF…