Abstract
2-Cys Peroxiredoxins (2-Cys Prx) are antioxidant enzymes able to decompose a variety of hydroperoxides (R-OOH) using a cysteine residue, named peroxidation cysteine (CP-SH), which is oxidized to cysteine sulfenic acid (CP-SOH) in the peroxide decomposition process. 2-Cys Prx possesses a second cysteine, (resolving cysteine - CR) that forms a disulfide bond during the catalytic cycle with …