Abstract
Aseptic loosening (bone resorption) and infection are some of the main causes leading to the failure of orthopaedic implants. Between other causes, aseptic loosening is attributed to stress shielding and/or to the over-activation of osteoclasts (bone resorbing cells) induced by the release of wear debris by the implant. Infection is due to the colonization of the surface of the implant by…