CV Lattes
Centro Infantil de Investigações Hematológicas Dr Domingos A Boldrini (CIB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Undergraduation in Ciências Biológicas from Universidade Estadual Paulista Júlio de Mesquita Filho (2008), master's in Genetics from Faculdade de Medicina de Ribeirão Preto (2012) and doctoral degree in Genetics from Universidade Estadual de Campinas (2019). International collaboration at University of Birmingham (UK), Centro de Investigaciones Biologicas (ES) e PennState Hershey Medical Center (USA). (Source: Lattes Curriculum)
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Acute leukemias (AL) are classified into acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). ALL has an excellent cure rate with current treatments, but 20% of patients experience recurrence. AML has a cure rate of 60-70 % in children. The discovery of new drugs and drug targets can help improve these ratios. Inhibitors of DNA methyltransferases (DNMTs) represent a group …
Acute lymphoblastic leukemia (ALL) has an excellent cure rate, but 20% of patients still relapsed. Relapsed leukemia cells show a higher expression of membrane-associated ATP-binding cassette (ABC) transporters when compared to leukemic cells at diagnosis. Overexpression of ABC transporters decreases intracellular drug levels, consequently limiting drug cytotoxicity since they pump drug m…
| 1 / 1 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
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