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ACIL-HIDRAZONAS COMO PROTÓTIPO DE NOVOS FÁRMACOS PARA LEUCEMIA LINFÓIDE AGUDA (LLA)

Document type:Patente
Inventor(s): Ricardo José Nunes; Alessandra Mascarello; Taisa Regina Stumpf; Paulo César Leal; José Andres Yunes; Carolina Pereira de Souza Melo; Rafael Renatino Canevarolo; Louise Domeneghini Chiaradia; Rosendo A. Yunes; Ângelo Bruneli Albertoni Laranjeira
Applicant: Universidade Federal de Santa Catarina (UFSC)
Deposit date: November 2011, 25
INPI register:
PI1107312-8
IPC: C07C 251/86 A61P 35/02 C07D 271/06
FAPESP's process: 09/04167-1 - Metabolomics of methotrexate resistance in acute lymphoblastic leukemia
Grantee:Rafael Renatino Canevarolo
Principal Investigator:José Andrés Yunes
Institution: Centro Infantil de Investigações Hematológicas Dr Domingos A Boldrini (CIB)
Support Opportunities: Scholarships in Brazil - Master
FAPESP's process: 12/11952-0 - Methotrexate resistance is directly associated with glutathione concentration in acute lymphoblastic leukemia cell lines
Grantee:Rafael Renatino Canevarolo
Principal Investigator:José Andrés Yunes
Institution: Centro Infantil de Investigações Hematológicas Dr Domingos A Boldrini (CIB)
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 08/02106-2 - IGFBP7 role in chemotherapy resistance of Pediatric Acute Lymphoblastic Leukemia
Grantee:Angelo Brunelli Albertoni Laranjeira
Principal Investigator:José Andrés Yunes
Institution: Centro Infantil de Investigações Hematológicas Dr Domingos A Boldrini (CIB)
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 12/03039-2 - IGFBP7 and insulin/IGFs in Childhood Acute Lymphoblastic Leukemia chemoresistance
Grantee:Angelo Brunelli Albertoni Laranjeira
Principal Investigator:José Andrés Yunes
Institution: Centro Infantil de Investigações Hematológicas Dr Domingos A Boldrini (CIB)
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 14/08247-8 - Preclinical studies of novel inhibitors of DNA methyltransferase in acute leukemia
Grantee:Nathalia Moreno Cury
Principal Investigator:José Andrés Yunes
Institution: Centro Infantil de Investigações Hematológicas Dr Domingos A Boldrini (CIB)
Support Opportunities: Scholarships in Brazil - Doctorate