CV Lattes
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Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduate at Farmácia Industrial from Universidade de São Paulo (1987), master's at Fármacos e Medicamentos FCFRP-USP from Universidade de São Paulo (1995) and ph.d. at Parasitology from Universidade Estadual de Campinas (1998). Has experience in Parasitology, focusing on Human Parasite Protozoology, acting on the following subjects: trypanosoma cruzi, biological activity, atividade biologica, farmácia and doença de chagas. (Source: Lattes Curriculum)
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Chagas disease (Trypanosoma cruzi) is a neglected disease that affects approximately 6 million people worldwide, especially in underdeveloped countries such as Brazil and also in non-endemic regions such as Europe, Japan, and Australia. Current chemotherapy therapy includes only two nitroheterocyclic drugs, benznidazole (BZ) and nifurtimox (NFX), which are effective in the acute phase of …
Chagas disease is part of the so-called Neglected Tropical Diseases group, affecting 8 million people worldwide according to the World Health Organization. Formerly endemic only in Latin America, it spread throughout the globe along with migratory movements, thus becoming a global health issue. Melatonin is a hormone produced by the pineal gland through the transformation, when there is n…
Cruzain, the main cysteine protease of Trypanosoma cruzi, is an essential enzyme for the life cycle of the parasite and has been used as a viable target for searching for enzyme inhibitors as drug candidates. The peptide mimetic compound K11777 inhibits cruzain at nanomolar concentrations, and acts by an irreversible inhibition mechanism. Analogs or derivatives K11777 usually contain elec…
This project aims to improve the supplying gas network to research laboratories; purchase of software to be installed on FCFRP´s server; acquisition of additional equipment to the confocal microscope acquired by FCFRP (multiuser platform) and adaptation of 10 research laboratories that perform activities with microorganisms included in Biosafety Level 2, in accordance to the standards of …
(Only some records are available in English at this moment)
Chagas disease (Trypanosoma cruzi) is a neglected disease that affects approximately 6 million people worldwide, especially in underdeveloped countries such as Brazil and also in non-endemic regions such as Europe, Japan, and Australia. Current chemotherapy therapy includes only two nitroheterocyclic drugs, benznidazole (BZ) and nifurtimox (NFX), which are effective in the acute phase of …
Chagas disease is a Neglected Tropical Disease (NTD) that affects 6 million people worldwide, with an incidence of 12,000 deaths annually. In addition to underreporting, the available treatments (benznidazole and nifurtimox) show low efficacy in the chronic phase of the disease, encouraging the search for new therapeutic schemes. Microemulsions are viable strategies for this, considering …
Chagas disease is part of the so-called Neglected Tropical Diseases group, affecting 8 million people worldwide according to the World Health Organization. Formerly endemic only in Latin America, it spread throughout the globe along with migratory movements, thus becoming a global health issue. Melatonin is a hormone produced by the pineal gland through the transformation, when there is n…
Chagas disease affects approximately 7 million people around the world as part of the group of Neglected Tropical Diseases (NTDs). The disease is endemic in Latin America, with the etiologic agent the protozoan Trypanosoma cruzi and its transmission occurs mainly through an insect vector, the triatomine. There are numerous studies involving this trypanosomiasis and increased adversity fou…
One hundred and five years after the discovery of Chagas disease, it is still a serious medical and social problem in Latin America due to its high morbidity. Chagas disease is caused by an intracellular protozoan, Trypanosoma cruzi (T. cruzi), and is a chronic and debilitating evolution. The limited number of drugs for this purpose has driven researchers to discover new drugs that can ac…
(Only some records are available in English at this moment)
Chagas disease is part of the so-called Neglected Tropical Diseases group, affecting 8 million people worldwide according to the World Health Organization. Formerly endemic only in Latin America, it spread throughout the globe along with migratory movements, thus becoming a global health issue. Melatonin is a hormone produced by the pineal gland in the absence of light. This hormone parti…
| 1 / 1 | Ongoing grants |
| 13 / 6 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 14 / 7 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 31 / 17 | All research grants and scholarships |
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