Abstract
Chagas disease (Trypanosoma cruzi) is a neglected disease that affects approximately 6 million people worldwide, especially in underdeveloped countries such as Brazil and also in non-endemic regions such as Europe, Japan, and Australia. Current chemotherapy therapy includes only two nitroheterocyclic drugs, benznidazole (BZ) and nifurtimox (NFX), which are effective in the acute phase of …