CV Lattes
Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Bachelor of Science by the 'University of Campinas - UNICAMP' (2014), taking part of the academic credits at the 'West Virginia University' and 'University of Wisconsin - Madison' (USA - 2013). Master of Science (2017) and PhD (2022) in Genetics and Molecular Biology (in Immunology) by UNICAMP, with part of his activites completed at the 'University of Cambridge/Babraham Institute' (UK - 2016) and 'Massachusetts Institute of Technology - MIT' (USA - 2020). Currently he is a postdoc at the 'Laboratory of Intestinal Immunity' at the 'IMAGINE Institute of Genetic Diseases' (France - 2022). He has experience in Immunology, Microbiology, Cellular Biology, Molecular Biology, and Genetics. (Source: Lattes Curriculum)
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Short-chain fatty acids (SCFAs) are products from the intestinal microbiota mainly produced by the fermentation of dietary fibers. SCFAs are found at high concentrations in the colon in where they play a fundamental energetic role in the epithelial cells, show important immunomodulatory effects, as well as they help to maintain the intestinal homeostasis through the regulation of the prol…
Short-chain fatty acids (SCFAs) such as butyrate, propionate and acetate are products of the dietary fibers fermentation from anaerobic bacteria in the gastrointestinal tract. These compounds, besides being an important energetic substrate, have many other actions in the organism including regulation of cellular differentiation, proliferation, apoptosis, and activation of the inflammatory…
Dietary fibers are fermented by the intestinal microbiota generating important metabolites known as short-chain fatty acids (SCFAs). These molecules act differently on various cell lineages through three main pathways: activation of G protein-coupled receptors (GPCRs), HIF-1± stabilization and inhibition of histone deacetylases (HDACs). Recently, it has been shown that specifically on int…
Short chain fatty acids (SCFAs, mainly acetate, propionate, and butyrate) are bacterial metabolites produced during fermentation of dietary fibers in the intestinal tract. These nutrients modulate the production of inflammatory mediators including chemokines, cytokines, and antimicrobial peptides by intestinal epithelial cells. In the present project, we aim to establish an in vitro model…
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