Abstract
Currently, nitrate is considered a source of NO. The nitrite may be converted to nitric oxide by enzymatic or chemical means. Works have demonstrated the antihypertensive effect of sodium nitrite in a model of hypertension 2 kidneys 1 clip (2K1C). However, the mechanisms responsible for the antihypertensive effect of nitrite were not fully elucidated. 2K1C hypertension occurs with a signi…