Abstract
Duchenne muscular dystrophy (DMD) is characterized by a progressive muscle disorder related to lack of dystrophin protein with increased Ca2+ uptake in the muscle fibers leading to muscle fiber necrosis, myonecrosis. Ca2+-operated channel entry (SOCE) belong to a complex of selective Ca2+ channels in the sarcolemma, including Orai1 and STIM1, which are present in the sarcoplasmic reticulu…