Abstract
It is known that thyroid hormone (TH) is essential for normal bone development. However, the mechanisms by which TH regulates this process are poorly understood. Recently, the sympathetic nervous system (SNS) was identified as a potent regulator of bone metabolism. Studies by our group have shown that ±2 adrenoceptor (±2-AR) mediates the SNSactions in the skeleton, as well as the TH-SNS i…