Abstract
G-protein-coupled receptors (GPCRs) belong to a superfamily of integral membrane proteins which have in their structure seven transmembrane alpha-helices, and for that reason, they are also known as 7 transmembrane receptors (7TMRs). 7TMRs constitute the largest class of cell surface receptors and they regulate a wide range of physiological and pathological processes, because of that, 7TM…