Abstract
Triple-negative breast câncer (TNBC), characterizad by lack of significant expression of the estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2), is a most aggressive subtype of breast cancer with poor prognosis and affects approximately 15% of cases of breast cancer. Among the major susceptibility genes for breast cancer are BRCA1 / BRCA…