CV Lattes
ORCID
Google Scholar Citations
Centro Infantil de Investigações Hematológicas Dr Domingos A Boldrini (CIB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
BSc in Molecular Biology from Universidade Estadual de Campinas - UNICAMP (2015) and MSc in Genetics and Molecular Biology at UNICAMP and Hospital Infantil Boldrini (2019). PhD Student in the Genetics and Molecular Biology program (IB - UNICAMP), at Boldrini Research Center, Additionally, works as a DTI-A researcher in a multicenter project at the Boldrini Children's Center.Has experience in Molecular Biology, acting on the following subjects: genome editing, acute lymphoblastic leukemia, CRISPR and TdT. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| More itemsLess items |
| TITULO |
| Articles published in other media outlets ( ): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
Approximately 9% of pediatric acute T-cell Lymphoid Leukemias (T-ALL) present a mutation with insertion of a cysteine residue in the justamembrane portion of the IL7Ra receptor, which leads to homodimerization and constitutive JAK/STAT signaling, contributing to leukemogenesis. The mutations are concentrated in a 26bp stretch of exon 6 of the IL7R gene (hotspot) and are characterized by l…
Acute lymphoblastic leukemia (T-ALL) of T cell represents 10% to 15% of cases of childhood ALL, and is caused by uncontrolled proliferation of T lymphocytes precursors. Nine percent of T-ALL have mutations in the extracellular juxtamembrane portion of the IL-7 receptor (IL7R) gene, caused by short insertion/deletions that ultimately add a cysteine residue. Presence of cystein was shown to…
| 2 / 2 | Completed scholarships in Brazil |
| Associated processes | |