Agustín Hernández López

CV Lattes ResearcherID ORCID Google Scholar Citations

Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal)
Birthplace: Espanha

I am a biochemist that has evolved into a cell biologist. Doctor by the University of Bristol (1996) obtained in the Department of Agricultural Sciences. My work now deals with veterinary cancer diagnostics using non-invasive liquid biopsies and *omics. In the past, I worked mostly on the interplay between ion pumps and membranes and how this affects cellular functions such as membrane traffic and fungal cell wall maintenance. In addition, I have experience in autophagy, cell death, pyrophosphate metabolism and cancer. In the last years, I opened a line on theoretical enzymology and biology analysis using Machine Learning. The aim of my studies was to understand non-structural functions of lipids in relation to sterol-related rare diseases and control of fungal proliferation.https://orcid.org/0000-0002-7884-8023 (Source: Lattes Curriculum)

News published in Agência FAPESP Newsletter about the researcher

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Research grants

Completed (most recent)

Abstract
Fungal parasites are among the most important pests affecting crop yields worldwide and are also the cause of some difficult to treat human diseases. In order to control pathogenic fungi, fungicides targeting the biosynthesis of ergosterol are widely used. However, the emergence of field resistances is hampering the efficacy of these compounds. Abnormal sterols of the kind accumulated by …
Mechanisms and consequences of intracellular traffic impairment by 8- and 14-dehydrosterols in fungal parasite models, AP.JP

Scholarships in Brazil

Completed (most recent)

Abstract
Parasitic fungi are responsible for ca 70% of plant diseases. Amine fungicides are a class of compounds essential for crop protection since they can control the proliferation of parasites affecting high value crops, for example yellow sigatoka, a parasite responsible for the loss of ca 50% of the banana crop yield in Brazil. The targets of this class of compounds are the enzymes sterol-8…
Study of the mechanisms impairing cell wall maintenance by abnormal sterols in fungi, BP.MS
Mechanisms and consequences of intracellular traffic impairment by 8- and 14-dehydrosterols in fungal parasite models, BP.JP

Virtual Library in numbers * Updated data on July 12, 2025

Total / Available in English

1 / 1	Completed research grants
2 / 2	Completed scholarships in Brazil
3 / 3	All research grants and scholarships

Associated processes

Most frequent collaborators in research granted by FAPESP

Leydi Roxana Gutiérrez Armijos

Keywords used by the researcher

Biochemistry Biological Sciences

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Abstract

Abstract