CV Lattes
Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Ciências Farmacêuticas (FCFAR) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Kaio Pini Santos in research grants and scholarships supported by FAPESP.
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Prostate cancer is the most incident neoplasm in men in the world. This neoplasm affects approximately 32% of the male population. Among the chemotherapeutics recently employed in therapy, we highlight the abiraterone, which acts in inhibition of the enzyme CYP17 (responsible for the synthesis of androgens). Abiraterone was approved by the Food and Drug Administration (FDA) in 2012 for us…
Tuberculosis (TB) is the major bacterial infectious disease in the world, leading to annual deaths of thousands of people and causing global economic losses of about 12 billion dollars a year. Only one drug was developed against multidrug-resistant strains since 1960 (bedaquiline) and the emergence of multi-drug-resistant cases of TB makes the current treatment ineffective. Rifampicin (RI…
Tuberculosis (TB) is the main infectious disease of bacterial origin in the world. Since 1966,rifampicin (RIF) is the drug of choice used in the treatment of TB. Typically, the drug is administered orally, thus susceptible to pre-systemic metabolism and drug interactions with other drugs; this can lead to a decrease of the treatment effectiveness and to an increase on the risk of resistan…
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