Abstract
Primary Sjogren's Syndrome (pSS) is a chronic systemic inflammatory disease, which mainly affects the lacrimal and salivary glands, leading to sicca syndrome. pSS has a probable autoimmune etiology, with the production of several autoantibodies such as Antinuclear Antibodies (ANA), anti-Ro/SS-A, anti-La/SS-B, Rheumatoid Factor (RF) and cryoglobulins. Recently, our group described a high f…