Abstract
Psoriasis (PSO) is an inflammatory dermatosis triggered by hyperproliferation and abnormal differentiation of T-cells able to release psoriatic cytokines (IL-17 and IL-22). In fact, IL-17 is the dominant cytokine that drives Tcell and keratinocytes activity in PSO, activating the proliferation of keratinocytes in the epidermis and boosting the maintenance phase of psoriatic inflammation. …