Abstract
Hereditary breast cancer accounts for approximately 7% of all cases of breast cancer. The main involved syndrome is a hereditary predisposition syndrome to Breast Cancer and Ovarian (HBOC), which is mainly due to the presence of germline mutations in the BRCA1 and BRCA2 genes. The vital cumulative risk for breast cancer in women with germline mutations in the BRCA1 and BRCA2 genes is 40% …