Abstract
The fibroblast growth factor - 2 (FGF2) acts as a mitogenic agent, but in some cellular contexts, has antiproliferative functions and may be an important tumor suppressor. In mice tumor cells (lineage Y1), FGF2 acts by inhibiting the transition G0 / G1 to S and irreversibly blocks the cells in G2 / M. Quantitative proteomic analyzes performed by our group identified several differentially…