Abstract
The infection in Chagas disease exhibit an acute phase, with high parasitaemia and generation of amastigote nests, and a chronic phase with cardiac nerve plexus injury and esophageal myenteric, caused by the immune action of Trypanosoma cruzi protozoan, leading to disease presentations like cardiomegaly, megacolon and megaesophagus. The mechanism of damage occurs by the formation of react…