A Ph.D. candidate in Functional and Molecular Biology at the University of Campinas (UNICAMP) / CNPEM, with an expected defense in September 2025, I possess a strong background in molecular biology, genetics, and biochemistry, built upon academic experiences in Brazil and abroad (University of Washington, USA; Washington Jefferson College, USA; and collaboration with CNRS, France). My doctoral research focuses on the biochemical and structural characterization of protein complexes involved in metabolic regulation, with expertise in advanced techniques such as mass spectrometry (HDX-MS). I demonstrate proficiency in molecular biology and genetic engineering, recombinant protein expression and purification, biochemical and biophysical analysis of macromolecules, and structural characterization, including in silico modeling and crystallography. My academic trajectory is marked by scholarships from funding agencies such as FAPESP and CAPES, as well as publications in high-impact scientific journals. (Source: Lattes Curriculum)
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The Metabolic Syndrome is a cluster of conditions that happens together. These conditions disrupt the body glycose levels homeostasis, which leads to a resistance to respond to insulin. The thiazolidinediones (TZDs) are the main drug for the treatment of Metabolic Syndrome. It targets the ligate-dependent nuclear receptor (RN) PPAR³ where it acts as a strong agonist. The PPAR³ is a key pl…
The aims proposed in the Young Researcher project address the regulation of gene expression of several transcription factors by Coup-TFII, to understand the molecular basis of embryonic cell differentiation. Once obtained at different modulation conditions of COUP-TFII expression, the embryoid bodies will be analyzed for the expression of tissue-specific gene markers and potential targets…
Metabolic syndrome is a cluster of conditions that happens simultaneously within the body and may lead to clinical conditions such as obesity and type II diabetes. This work focus on the structural investigation of the deacetylase SIRT1 and the nuclear receptor PPAR³, a master regulator of adipogenesis and glucose homeostasis. Recently studies demonstrate that PPAR³ controls adipogenesis …
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| 1 / 1 | Completed scholarships abroad |
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CV Lattes
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