Abstract
Recently, our group developed an ultra-sensitive technology based on HPLC / micro HPLC / mass spectrometry to measure DNA oxidation and modifications induced by reactive aldehydes. Our main project is to investigate the use of these lesions as redox stress biomarkers. The present project aims to compare DNA lesions (8-oxo-7,8-dihydro-2'-deoxyguanosine, 1,N2-ethene-2'-deoxyguanosine and 1,…