CV Lattes
Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Karen Cristine de Oliveira Santos Ferreira in research grants and scholarships supported by FAPESP.
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Adipose tissue is one of the important insulin-dependent tissue responsible for glucose uptake. Hypertrophic adipocytes may undergo lysis and recruit macrophages, resulting in release of pro-inflammatory cytokines such as TNFa, that interferes with the insulin signaling pathway and result in insulin resistance: that is one of the trigger of type 2 diabetes mellitus (DM2). Osteoprotegerin …
The soluble and secreted protein Osteoprotegerin (OPG) is a decoy receptor for RANKL (receptor activator of NFkB ligand) that inhibits its binding to the membrane bound receptor RANK (receptor activator of NFkB). High serum osteoprotegerin (OPG) level has been associated with type 2 diabetes mellitus (T2DM), but the biological explanation for the rise of OPG level remains unclear: Is OPG …
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