CV Lattes
Ministério da Ciência, Tecnologia e Inovação (Brasil). Centro Nacional de Pesquisa em Energia e Materiais (CNPEM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Biomedical graduate from the Federal University of Paraná (UFPR), qualified in Molecular Biology, with a PhD in Genetics and Molecular Biology from the State University of Campinas (UNICAMP). From 2017 to 2018, with a Fapesp Research Internship Abroad (BEPE) fellowship, he performed an internship at the MD Anderson Cancer Center, in Houston, Texas, USA, under the supervision of Dr. George Calin, in the non-coding RNAs laboratory, perfecting RNA manipulation techniques and cell culture and scientific writing. He recently completed his doctorate at the State University of Campinas (Unicamp) for the postgraduate program in Genetics and Molecular Biology, held at the National Biosciences Laboratory (LNBio/CNPEM). He specialized in understanding the role of immune system cells in the tumor microenvironment, using cell co-culture techniques, extraction of primary bone marrow cells, in vivo breast tumor induction assays and analysis of samples by immunohistochemistry, ELISA and flow cytometry. He currently works as a specialist in technological development at LNBio with Dr Kleber Franchini's group. (Source: Lattes Curriculum)
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Cancer is a disease in which its main characteristic is the continuous cell proliferation. To sustain the high proliferative rate, tumor cells have an increased demand for biosynthetic precursors used in the synthesis of macromolecules that compose the daughter cells. Therefore, tumors consume a large amount of glucose and glutamine, mainly. The increase in glutamine consumption, besides …
Our main goal is to understand the role of GLS2 on breast cancer progression. For such, we want to answer the following questions:Do M1 and M2 macrophages influence in vitro metastasis of GLS2 expressing cells? GLS2 has been more often linked to anti-tumorigenic effects, mainly in hepatocarcinomas and gliomas. We found a link between GLS2 expression and diminished breast cancer patient s…
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