Abstract
The hypothalamus-pituitary-gonads axis is responsible for neuroendocrine regulation of reproduction, by the action of GnRH, LH and FSH hormones. Kisspeptin, produced by Kiss1 neurons localized in hypothalamus - more specific in arcuate (Arc) and Anteroventral Periventricular nucleus (AVPV), acts together with GPR54 receptor as a exterior signals processor for reproduction, modulating GnRH…