CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
BSc in Biological Sciences from Universidade Estadual de Campinas (2003), MSc (2004) and PhD (2011) in Biochemistry from Universidade de São Paulo (USP). Was a post-doc at the Institute of Physics/USP (2011-2014) and at the Peter Doherty Institute/University of Melbourne (2015). Has experience in Enzimology, Biophysics and Immunology. Works with biocolloids and their applications in vaccine, drug and DNA delivery. Currently is Adjunct Professor of Biophysics at the Federal University of São Paulo (School of Medicine - Unifesp/EPM) and Group Leader in the Graduate Program of Molecular Biology. Co-Chair of the Brazilian Chapter of the American Chemical Society (2022-2023). (Source: Lattes Curriculum)
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Vaccine adjuvants intensify immune responses against co-inoculated antigens and depend on biophysical properties to be efficient. There is great pharmaceutical interest in developing new adjuvants that are able to activate CD1d-restricted T cells, because they recognize lipid antigens and influence immune responses related to several pathogens, autoimmune diseases and cancer. Due to its p…
The C24:1 sulfatide belongs to a family of sulfoglycolipids that perform several important biological functions. It is recognized as an antigen by CD1-restricted T cells; the use of a suitable carrier might result in the activation of these cells with potential immunotherapeutic applications. The cationic lipid DODAB, which has been extensively used as an immunoadjuvant, may serve as an a…
Vaccine adjuvants intensify immune responses against co-inoculated antigens and depend on biophysical properties to be efficient. Disialoganglioside GD3 is an endogenous glycolipid overexpressed by cancer cells and is recognized as an antigen by immune cells that are able to trigger important responses in the activation of cell death processes against cancer. Due to its physical and chemi…
DiC14-amidine and DODAB are cationic lipids that present biological applications in nucleic acid delivery to cells and in the generation of immune responses. DiC14-amidine has two titratable groups (amine and amidine) and its bilayer structure is sensitive to pH. DODAB has a quaternary ammonium group with a permanent charge that is independent of pH. The aim of this project is to characte…
| 1 / 1 | Completed research grants |
| 4 / 3 | Completed scholarships in Brazil |
| 5 / 4 | All research grants and scholarships |
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