CV Lattes
Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Ciências Biológicas from Centro Universitário São Camilo (2006), master's at Biochemistry from Universidade Federal de São Paulo (2009) and doctorate at Biochemistry from Universidade Federal de São Paulo (2013). Has experience in Pharmacology, focusing on Pharmacology Molecular Biochemistry (Source: Lattes Curriculum)
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Recent studies on the structure-activity of the kinin B1 receptor (B1R) revealed that important residues for its binding to des-Arg9-bradykinin (DBK) are homologous to those in the interaction between angiotensin II and the angiotensin II (AngII) type I receptor (AT1R). Several studies have shown that the ammonium group of Lys199 (512) located in the helix V of AT1R interacts with the car…
Kinins are proinflammatory peptides that act as local hormones and activate the release of endothelium-derived relaxing factor and prostaglandins, increase vascular permeability, contract or relax smooth muscle and provoke pain. Most of these effects are mediated by the B2 receptor, which belongs to a family of peptide hormone receptors linked to G proteins (for a review, see Leeb-Lundber…
| 2 / 2 | Completed scholarships in Brazil |
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